产品货号：
Z21465
中文名称：
NDUFAF2抗体
英文名称：
Anti-NDUFAF2 Antibody
产品规格：
0.1mg
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-NDUFAF2 Antibody |
| 指标别名 | B17.2 like;B17.2L;mimitin;Mimitin;mitochondrial;MMTN;NDUFA12 like protein;NDUFA12L;NDUFAF2 |
| 克隆性 | Polyclonal |
| 检验物种 | human |
| 应用范围 | ELISA,WB,IF |
| 基因名称 | NDUFAF2 |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | Mimitin antibody was raised against a 14 amino acid synthetic peptide from near the carboxy terminus of human Mimitin.The immunogen is located within the last 50 amino acids of Mimitin. |
| 计算分子量 | 20kDa |
| 成分 | Mimitin Antibody is supplied in PBS containing 0.02% sodium azide. |
| 纯化方式 | Mimitin Antibody is affinity chromatography purified via peptide column. |
| 浓度 | 1mg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 4℃可保存3个月，-20℃可保存1年。 |
| 背景资料 | Mimitin,a small mitochondrial protein,whose transcription is directly stimulated by c-Myc,is highly expressed in 80% of esophageal squamous cell carcinomas (ESCC).Suppression of Mimitin expression by RNA interference had no effect in cancerous cell lines such as human cervical carcinoma or hepatocarcinoma cell lines,but caused a decrease in cell proliferation in human glioblastoma,embryonic lung fibroblastic cells,and ESCC,suggesting Mimitin may play a special role in these types of cells.Mimitin expression is also regulated by MAPK kinases and IL-1,but not through the NF-百B-related pathway.It will interact with the microtubular protein MAP1S and can affect the activities of caspase-3 and -7 in cells stimulated to develop apoptosis.Other experiments suggest that Mimitin also acts as a molecular chaperone for the assembly of the mitochondrial complex I. |
| Uniprot ID | Q8N183 |
| 基因名全称 | NADH dehydrogenase (ubiquinone) 1 alpha subcomplex,assembly factor 2 |
| 蛋白名全称 | NADH dehydrogenase (ubiquinone) 1 alpha subcomplex,assembly factor 2 |
| 推荐稀释比 | Mimitin antibody can be used for detection of Mimitin by Western blot at 1 ～ 2μg/mL.Antibody can also be used for immunoflourescence starting at 20μg/mL.For immunofluorescence start at 20μg/mL.Antibody validated:Western Blot in human samples and Immunofluorescence in human samples.All other applications and species not yet tested. |
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